Going over the edge for Worldwide Cancer Research
Twenty students, research scientists and Worldwide Cancer Research staff tackled a daunting 200ft abseil from Avon George on Wednesday 4th of March and raised over £2,000 for our vital early stage cancer research.
The team of courageous Bath students were recruited by Worldwide Cancer Research Student Events Coordinator Anna Howarth, a former Student of Bath University;
“Bath gave me so much as a city and a university and has continued to do so in my current role. I was so happy to take a team from the university on this challenge to raise money for our research. They really enjoyed the challenge and there was a lot of smiling faces, once they get to the bottom.”
Professor Threadgill and Dr Nathubhai who are current Worldwide Cancer Research grant holders also took the plunge to lend their support. They are using their Worldwide Cancer Research grant to make potential new anticancer drugs that will act on specific proteins which are present at abnormally high levels in cancer cells. This makes them good targets to selectively kill cancer cells, while leaving healthy cells relatively unharmed. The specific shapes of these proteins are already known and the researchers are using computer software to design potential new drugs in “virtual reality”, making the discovery process more efficient and cutting out laboratory work on those chemicals which can be predicted to be ineffective. They will then test the the drugs to see if they actually work on the proteins (known as Tankyrases) but on no other useful proteins. Professor Threadgill and Dr Nathubhai hope that the completion of this project will provide one or more potential anticancer drugs which work by new mechanisms of action.
“I’ve been researching new cancer drug treatments for over twenty years and Worldwide Cancer Research has funded a lot of this work. Just recently, we have had two projects which are showing promise; one in stopping cancer cells dividing, the other in prostate cancer. Support from Worldwide Cancer Research has been key in both discoveries.”
You can read more about Professor Threadgills work at http://www.worldwidecancerresearch.org/project/designing-new-anti-cancer-drugs/