Worldwide Cancer Research Menu

Delivering immunotherapy to the heart of lung cancer

  • Researcher: Professor Kairbaan Hodivala-Dilke
  • Institution: Queen Mary University of London, England
  • Award Amount: £208,131 for 3 years from 1st April 2019
  • Cancer Type: Lung Cancer
Delivering immunotherapy to the heart of lung cancer
Non-small cell lung cancer (NSCLC), the most common type of lung cancer, has no cure and the overall survival rate is estimated to be only 20 per cent. It’s therefore critical that research uncovers new ways to treat the 1.7 million people diagnosed with NSCLC each year. Immunotherapy, a treatment that acts by turning the patient’s immune system against the tumour, holds real promise for treating NSCLC, but is held back by our inability to target the treatment directly at the tumour.

Professor Kairbaan Hodivala-Dilke has previously found that by using low doses of a drug originally designed to cut off the blood supply to a tumour, they are, counterintuitively, able to increase blood flow to the tumour and increase the level of chemotherapy that reaches the tumour. This odd finding has led Professor Hodivala-Dilke to investigate if a similar approach could be used to target the cancer-killing effects of immunotherapy directly at the tumour.

Professor Hodivala-Dilke and her team, based at Queen Mary University of London, England, aim to test a new drug in pre-clinical studies to see if it can boost the effects of immunotherapy in NSCLC. If successful, her team hopes that they will be able to take the new drug forward into clinical trials to treat lung cancer patients.

Showing: All projects

The Research That Is Happening Right Now

Explore current projects to see how far-reaching our research is from a global perspective.

Projects per page: 31020

Our Impact

See the difference our research projects make.

Philosophy
Our philosophy is very simple: if we believe a project can make a difference in the fight against cancer then we will award a grant to make it happen. We’re not interested in national borders or any kind of geographical bias, just the most promising proposals. And that’s the very reason we ask t...
Read more
Life in the Lab
Supporters often ask us what type of projects their donations are funding. What does a typical day in the life of a cancer researcher look like? To answer these questions and give you an insight into the vital work your support helps us to fund, we've put together this short video....
Read more