Developing targeted treatments for mesothelioma – the asbestos cancer
- Researcher: Dr Carsten Hansen
- Institution: University of Edinburgh, Scotland, UK
- Award Amount: £201,618 for 3 years from 1st June 2019
- Cancer Type: Mesothelioma
Dr Carsten Hansen, based at the University of Edinburgh, Scotland, is interested in a molecular signalling network found in cells called “The Hippo Pathway”. This network of proteins helps to convey messages around the cell that tell the cell to grow and divide. When Hippo Pathway signals are sent out too much it can contribute to make cells cancerous.
Dr Hansen and his team are studying the Hippo network of proteins to understand exactly what goes wrong in mesothelioma cancer cells. Using this information, and building on previous research, they plan to find potential drug molecules, which target aspects of the Hippo network that might one day provide therapeutic benefit for patients
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