Worldwide Cancer Research Menu

How does Birt-Hogg-Dubé syndrome develop into cancer?

  • Researcher: Professor Maurice van Steensel
  • Institution: Universiteit Maastricht
  • Award Amount: £153,409 for 2 years from August 2011
  • Cancer Type: General Cancer Research
How does Birt-Hogg-Dubé syndrome develop into cancer?

Birt-Hogg-Dubé (BHD) syndrome is a rare disorder where people develop non-cancerous growths on their faces and are at risk of developing kidney cancer. Patients are also at risk of developing cysts in their kidneys, liver and lungs. It is known that BHD is caused by alterations in a gene called FLCN but it is unclear how this alteration can cause cysts and cancer. Dr van Steensel believes that formation of the cysts precedes the cancer and he is using his Worldwide Cancer Research grant to investigate how lack of FLCN causes cysts to develop.

Showing: All projects

The Research That Is Happening Right Now

Explore current projects to see how far-reaching our research is from a global perspective.

Projects per page: 31020

Our Impact

See the difference our research projects make.

Philosophy
Our philosophy is very simple: if we believe a project can make a difference in the fight against cancer then we will award a grant to make it happen. We’re not interested in national borders or any kind of geographical bias, just the most promising proposals. And that’s the very reason we ask t...
Read more
Life in the Lab
Supporters often ask us what type of projects their donations are funding. What does a typical day in the life of a cancer researcher look like? To answer these questions and give you an insight into the vital work your support helps us to fund, we've put together this short video....
Read more