Identifying and characterising the cells in tumours of the mouth and lip that allow the development of secondary tumours
- Researcher: Dr Salvador Aznar-Benitah
- Institution: Institute for Research in Biomedicine (IRB Barcelona)
- Award Amount: £224,177 for 3 years from September 2013
- Cancer Type: Oral Cavity and Lip Cancer
There is still much that scientists don’t understand about the tumour cells that are able to break away from the original tumour. Dr Aznar-Benitah is therefore using his Worldwide Cancer Research grant to study these cancer cells in tumours in the lining of the mouth and lips. The team have already identified a group of cells within these tumours that may be the cells of origin. They are using this grant to further investigate what makes these cells unique from the rest of the tumour cells and what characteristics enable them to break away and start new tumours.
The team will be using mouse models of the disease as well as studying cells from samples taken directly from human tumours of the mouth and lip lining. As this project involves studying how cells move from the mouth and lip to other places in the body it simply would not be possible without the use of mouse models. If Dr Aznar-Benitah is able to identify how these tumour cells break away and start new ones his team, or other scientists, could then work on finding ways to stop the process from happening. If scientists were able to stop tumours from spreading, successful treatment would be much easier to achieve.
Showing: All projects
The Research That Is Happening Right Now
Explore current projects to see how far-reaching our research is from a global perspective.
See the difference our research projects make.
Our philosophy is very simple: if we believe a project can make a difference in the fight against cancer then we will award a grant to make it happen. We’re not interested in national borders or any kind of geographical bias, just the most promising proposals. And that’s the very reason we ask t...Read more
Life in the Lab
Supporters often ask us what type of projects their donations are funding. What does a typical day in the life of a cancer researcher look like? To answer these questions and give you an insight into the vital work your support helps us to fund, we've put together this short video....Read more