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Improving models for the study of mixed lineage leukaemia

  • Researcher: Professor Eric So
  • Institution: King's College London
  • Award Amount: £230,006 for 3 years from April 2012
  • Cancer Type: General Cancer Research
Improving models for the study of mixed lineage leukaemia
Despite the difference in appearance, when we are looking at the DNA level we are quite similar to animals such as mice. Before any treatments can ever be trialled in humans, the early research and development is done in animals first. Researchers use animals to discover how the cancer begins in the first place, how it is able to grow and how and where it spreads to. It is therefore important to have animal models that closely mimic human cancers so that any research carried out is accurate and relevant for human cancers. Professor So, who has been funded by Worldwide Cancer Research for the past 6 years through one of our prestigious Research Fellowships, is using his new Worldwide Cancer Research grant to develop a mouse model that mimics human mixed lineage leukaemia (MLL) leukaemia. He will be using cutting edge techniques and hopes that the resulting mouse model will prove a "proof of principal" and help with the development of other cancer models in the future that are cheaper and quicker than the current techniques.
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