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Investigating how stomach cancer begins and how to stop it

  • Researcher: Professor Andrew Giraud
  • Institution: Murdoch Childrens Research Institute, Parkville, Australia
  • Award Amount: £246,134 for 3 years from January 2014
  • Cancer Type: Stomach Cancer
Investigating how stomach cancer begins and how to stop it
Despite the progress being made in cancer research, stomach cancer is still one of the cancers with a low survival rate. In 2008 almost 990,000 people around the world were diagnosed with stomach cancer and 738,000 people died from the disease. Stomach cancer is strongly linked to prolonged inflammation of the lining of the stomach and changes in the bacteria found there. Professor Andrew Giraud is investigating the role a molecule called IL-11 plays in stomach cancer. He will be using mice models which mimic one of the early events preceding human stomach cancer caused by bacteria. A major focus of this work will not only be to understand how cancer begins, but to identify potential ways to stop the process. He hopes to take it further and find small molecules which could actually prevent stomach cancer occurring. If successful, and after extensive further research, his findings could potentially be used to try and treat people with stomach cancer.
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