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Investigating the communication pathways within our cells

  • Researcher: Dr Alexander Hergovich
  • Institution: University College London
  • Award Amount: £207,966 for 4 years from June 2011
  • Cancer Type: General Cancer Research
Investigating the communication pathways within our cells
Every cell contains thousands of genes. These act as blueprints to produce proteins which carry out all the functions within the cells. The genes and proteins are divided into a series of different pathways, each controlling a group of activities such as cell growth or death. Many of these genes and proteins, and therefore pathways, are altered in cancer cells. These alterations make the pathways operate differently, causing the cells to grow and divide rapidly and forming a tumour. One protein often altered in cancer is the hMOB2 protein which forms part of the hippo pathway. Its exact role in cancer formation is unclear and this is the focus of Dr Hergovich's Worldwide Cancer Research grant.
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