Worldwide Cancer Research Menu

Investigating the control checkpoints within our cells

  • Researcher: Dr Danny Huang
  • Institution: Beatson Institute for Cancer Research
  • Award Amount: £165,590 for 3 years from June 2012
  • Cancer Type: General Cancer Research
Investigating the control checkpoints within our cells
Cancer can be caused by damage to the DNA inside our cells. This damage can be due to many things such as UV from sunlight or the DNA can become altered or damaged as it is being copied when the cells are growing and dividing to form new cells. All cells have mechanisms to detect and repair this DNA damage, to prevent them becoming cancerous. These detection and repair mechanisms can sometimes become altered or faulty which allows the DNA damage to remain, allowing the cells to become cancerous and tumours to develop. Dr Danny Huang is using his Worldwide Cancer Research grant to study a molecule involved in these mechanisms called Chk1. In particular he will be investigating which other molecules Chk1 interacts with and how they control whether Chk1 is turned on or off. Dr Huang hopes that his findings will help researchers understand how damaged DNA can be allowed to remain and its role in cancer progression.
Showing: All projects

The Research That Is Happening Right Now

Explore current projects to see how far-reaching our research is from a global perspective.

Projects per page: 31020

Our Impact

See the difference our research projects make.

Philosophy
Our philosophy is very simple: if we believe a project can make a difference in the fight against cancer then we will award a grant to make it happen. We’re not interested in national borders or any kind of geographical bias, just the most promising proposals. And that’s the very reason we ask t...
Read more
Life in the Lab
Supporters often ask us what type of projects their donations are funding. What does a typical day in the life of a cancer researcher look like? To answer these questions and give you an insight into the vital work your support helps us to fund, we've put together this short video....
Read more