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Investigating the molecules involved in bowel cancer

  • Researcher: Dr Axel Behrens
  • Institution: London Research Institute
  • Award Amount: £120,942 for 2 years from May 2012
  • Cancer Type: Bowel Cancer
Investigating the molecules involved in bowel cancer
Worldwide, bowel cancer is the third most common cancer type, an estimated 1.24 million people were diagnosed with the disease in 2008. Incidences of bowel cancer are highest in the Western world. But with westernisation of the diet in several Asian countries new cases are increasing. Age is the most likely cause of bowel cancer, and what we eat has plays a large part in the development of bowel cancer, but we do not yet fully understand the mechanisms that are involved in causing the disease. Dr Behrens is using his Worldwide Cancer Research grant to investigate the communication pathways inside our cells that can lead to bowel cancer. In particular he is focussing on a molecule called PRMT1 and whether switching it off with drugs could help in the treatment of bowel cancer.
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