The role of histone H3 methylation in cancer
- Researcher: Dr Amir Eden
- Institution: The Hebrew University of Jerusalem
- Award Amount: £143,100 for 3 years from January 2013
- Cancer Type: General Cancer Research
Dr Eden and his team are studying methylation of a gene scaffolding protein, called histone H3. Methylating histone H3 seems to control whether the surrounding DNA is methylated or not. They have developed a system which allows them to study histone H3 methylation, and they will use their Worldwide Cancer Research grant to study the role this plays in changes that are associated with cancer. This will produce important new information about how the activity of key genes can go wrong in cancer.
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