Worldwide Cancer Research Menu

Three-pronged attack on kidney cancer

  • Researcher: Professor Hardev Pandha
  • Institution: University of Surrey, England
  • Award Amount: £198,670 for 3 years from 1st April 2019
  • Cancer Type: Kidney Cancer
Three-pronged attack on kidney cancer
Each year there are around 400,000 people worldwide diagnosed with kidney cancer. Survival rates have improved dramatically over the last 40 years, but, in the UK, only half of people will still be alive 10 years after diagnosis. New immunotherapy treatments, such as the drug nivolumab, have helped give patients with advanced kidney cancer a longer and better quality of life, but it only seems to work in around a quarter of patients.

Professor Hardev Pandha, based at the University of Surrey, England, wants to make drugs like nivolumab work for as many patients as possible. His team are investigating a new three-pronged combination therapy that they hope will ultimately improve how nivolumab works. They are using a genetically modified virus that has been designed to help the immune system target and destroy cancer cells, alongside a second drug that “starves” the cancer cells of certain nutrients. Combining these two drugs with nivolumab could make this treatment more effective for more people. All of these drugs are currently being tested in patients so, if successful, this work could be rapidly taking forward into clinical trials.

This project has been made possible thanks to a co-funding partnership with Kidney Research UK.

Showing: All projects

The Research That Is Happening Right Now

Explore current projects to see how far-reaching our research is from a global perspective.

Projects per page: 31020

Our Impact

See the difference our research projects make.

Our philosophy is very simple: if we believe a project can make a difference in the fight against cancer then we will award a grant to make it happen. We’re not interested in national borders or any kind of geographical bias, just the most promising proposals. And that’s the very reason we ask t...
Read more
Life in the Lab
Supporters often ask us what type of projects their donations are funding. What does a typical day in the life of a cancer researcher look like? To answer these questions and give you an insight into the vital work your support helps us to fund, we've put together this short video....
Read more