Understanding why children with Down Syndrome are at risk of leukaemia
- Researcher: Dr Andrea Ditadi
- Institution: Fondazione Centro San Raffaele, Milan, Italy
- Award Amount: £249,500 for 3 years from 1st January 2019
- Cancer Type: Blood Cancer, Leukaemia
Dr Andrea Ditadi and his team based at Fondazione Centro San Raffaele, Milan, Italy, propose to uncover this mystery by carrying out in-depth studies on pluripotent stem cells – the cells that “give birth” to all the cell types in our body. By studying these cells they want to find out how the cells of the blood system develop in Down Syndrome and use this to identify the cells responsible for AMKL development. This fundamental understanding of the biology behind this phenomenon will ultimately lead to new ways to diagnose and treat AMKL.
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