Bowel cancer – everything you need to know

2nd April 2021

Here’s a helpful guide to everything you should know about the disease.

What is bowel cancer? 

Bowel cancer begins in the large bowel - the colonThat’s why, depending on its location, it can also be called colon or rectal cancerIt starts when abnormal cells multiply and grow too quickly in an uncontrolled way.  

Bowel cancer is one of the most common cancers in the UK with around 43,000 people diagnosed each yearThat’s 1 in 15 men and 1 in 18 women.

What causes bowel cancer? 

The exact reason as to why some cells turn cancerous is not known, but there are certain risk factors that can make it more likely for a person to develop bowel cancer. That’s why experts think that roughly half of bowel cancer cases are preventable. 

Bowel cancer usually starts in a polyp, which is a clump of cells on the inner lining of the bowel. Polyps are very common, especially in older people, and only very few develop into bowel cancer.   

While there is never any guarantee, there are some risk factors that have been linked to the development of bowel cancer: 


Age is a big risk factor for bowel cancer. 9 in 10 people that develop bowel cancer are over the age of 60. 

Family history 

A person might be more likely to develop bowel cancer when they have close family members that were diagnosed with bowel cancer. 


Low intake of fibre plays a major role in the development of bowel cancer. A diet high in red and processed meat can also significantly increase the risk of bowel cancer in a person. That’s why the NHS recommends that all people currently eating more than 90g of red and processed meat (cooked weight) cut down to 70g or less. For more advice on how to eat a healthy and balanced diet, check out the NHS’s advice on living well.

Alcohol, smoking, inactivity and obesity 

Drinking alcohol, smoking, inactivity and excess weight have all been linked to an increased risk of bowel cancer. These lifestyle habits are also implicated in the development of many other cancers. To find out more about these risk factors for cancer, check out the NHS site. 

Digestive and genetic conditions 

Some digestive disorders, including Crohn’s disease and ulcerative colitis have been linked to the development of bowel cancer. There are also rare genetic conditions, such as Lynch syndrome, that can lead to an increased risk of developing the disease. People with these conditions are usually monitored more closely for the development of bowel cancer. 

What are the symptoms of bowel cancer? 

Symptoms can be subtle, but if you experience 1 or more of the ones listed below for more than 4 weeks, have it checked out by your GP 

  • persistent change in bowel habits (e.g, going more often, looser and runnier stool) 
  • abdominal pain, discomfort or bloating after eating 
  • blood in the stool 
  • in cases where the bowel might be obstructed, symptoms can include severe abdominal pain, unintentional weight loss, swelling of the abdomen and being sick 

Having these symptoms does not mean that a person has bowel cancer, but if they are persistent, should always be checked out by a GP. It is important not to wait until the next bowel screening test (see below) to see a health care professional. 

How is bowel cancer diagnosed? 

Bowel cancer can be diagnosed only by visiting a health professional. 

The NHS offers home screening tests and while these home screening test cannot diagnose bowel cancer; they can detect small amounts of blood - a potential sign for bowel cancer - in a stool sample. These kits are offered to people aged 60 – 74 every 2 years in most parts of the UK. Scotland is the only exception, where those aged 50+ will receive a home testing kit every two years. 

These are incredibly important tests to participate in as they can identify people who might benefit from more testing. You can find out more about bowel screening on the NHS website. 

How is bowel cancer treated? 

Treatment varies from patient to patient. It may depend on which part of the bowel is affected, as well as the stage of the cancer, but surgery remains the main treatment for many patients. This can be combined with chemo- and/or radiotherapy and other biological treatments.  

If the cancer is found early enough, bowel cancer can be stopped from coming back, but advanced cancer can spread – especially to the liver – and become resistant to treatment. Currently 57% of patients survive 10 years or longer after their diagnosis. 

Our researchers are working hard on improving these survival rates - by building mini-tumours, understanding why drugs stop working in some cases and finding new ways to treat advanced bowel cancer

It’s thanks to our supporters that we’re able to start new cancer cures. With your help, we can fund more bowel cancer research around the world. 


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