Research projects

Active Portugal

Leukaemia

How does our bone marrow help leukaemia to grow?

This project explores if ‘niches’ in our bone marrow might help to support leukaemia cells to grow, and if this could be a new target for leukaemia treatments. 

Researcher: Dr Delfim Duarte

Understanding how bone marrow ‘niches’ can help leukaemia cells to grow

Active France

General cancer research

Can we stop cancer coming back by learning more about cancer cells?

Researchers are exploring the role cancer stem cells play in cancers coming back after treatment, to try to stop this happening so often in patients. 

Researcher: Dr Silvia Fre

Stopping cancer coming back by better understanding how cancer stem cells behave

Active France

Brain cancer

Can we stop brain tumour getting new ‘batteries’ from brain cells?

Exploring if stopping glioblastoma cells taking in new ‘batteries’ from healthy cells could be a new way to treat this particularly aggressive cancer. 

Researcher: Dr Rubén Quintana-Cabrera

Preventing glioblastoma tumours from importing new ‘batteries’ from brain cells
Professor Sophia Karagiannis Team

Active United Kingdom

Melanoma

How can we help treatments work for more melanoma patients?

Immunotherapy currently does not work for half of all melanoma patients. This project hopes that understanding allergic reactions could lead to new solutions.

Researcher: Professor Sophia Karagiannis

Atchoo! Can understanding allergic reactions lead to new cancer treatments?

Active Israel

General cancer research

Can we stop cancer by targeting cancer cell batteries?

Discovering how cancer cells generate the energy they need and whether we can stop this process, to find possible new targets for cancer treatments.

Researcher: Dr Barak Rotblat

Powering down: Targeting the cancer cell batteries to stop cancer

Active USA

Leukaemia

Can we find a new treatment for a rare but aggressive blood cancer?

This project is finding out more about a key molecule in the growth of acute myeloid leukaemia to hopefully reveal clues to better, more effective treatments.

Researcher: Dr Bruno Di Stefano

Targeting cancer’s weak spot – a new vulnerability for leukaemia

Active Italy

Lung cancer

Can bacteria in our lungs make cancer treatment more effective?

Researchers are hoping to pave the way towards much needed new lung cancer therapies using helpful microbes to boost therapies and improve survival rates.

Researcher: Dr Chiara Ambrogio

Mighty microbes: can bacteria in our lungs make cancer treatment more effective?

Active Australia

General cancer research

Can we prevent cancer cells from surviving and growing?

By furthering our knowledge about the thousands of genes that are contained in each cancer cell, this project aims to find brand new combinations of cancer drugs. 

Researcher: Professor Ricky Johnstone

Flipping the molecular master switches that drive cancer

Active Australia

Breast cancer

Why do breast cancer treatments work on some patients but not others?

This project could uncover new ways to help predict who would benefit from an existing breast cancer treatment, and improve its effectiveness for more patients.  

Researcher: Professor Pieter Eichhorn

Improving the effectiveness of a breast cancer treatment for more patients