Our research projects

We won't stop until cancer does

Project
Uncovering how a faulty BRCA2 gene causes breast cancer to develop
Cancer type
Breast cancer
Research goal
How cancer develops
Project
How genetic mutations in healthy blood cells can help drive lymphoma development
Cancer type
Non-Hodgkin lymphoma
Research goal
How cancer works
Project
Understanding why treatments don’t work for some non-smoking lung cancer patients
Cancer type
Lung cancer
Research goal
Overcoming treatment resistance
Project
Using AI to predict drug resistance mutations in breast cancer
Cancer type
Breast cancer
Research goal
Improving diagnosis
Project
Targeting the gut microbiome to make immunotherapies more effective
Cancer type
Bowel cancer
Research goal
How cancer works
Project
Model brains: Using fruit flies to understand how brain tumours spread
Cancer type
Brain
Research goal
How cancer works
Project
Understanding why treatment resistance develops
Cancer type
General cancer research
Research goal
Overcoming treatment resistance
Project
Targeting nuclear rupture: a new weakness to exploit in cancer
Cancer type
Breast
Ovarian
General cancer research
Research goal
New targeted treatments
Project
Improving our understanding of how to treat kidney cancer
Cancer type
Kidney
Research goal
How cancer works
Project
What’s the risk? Predicting endometrial cancer using genetics and measures of obesity
Cancer type
Endometrial cancer
Research goal
Cancer prevention
Project
Understanding how melanoma adapts to spread and seed new tumours
Cancer type
Melanoma
Research goal
How cancer works
Project
A new approach to eradicate pancreatic tumours
Cancer type
Pancreatic cancer
Research goal
New targeted treatments
Project
Understanding how immune cells participate in the spread of pancreatic cancer
Cancer type
Pancreatic cancer
Research goal
How cancer works
Project
Developing a new targeted treatment for lung cancer
Cancer type
Lung cancer
Research goal
New targeted treatments
Project
Blocking bio-parcels to stop breast cancer spreading
Cancer type
Breast cancer
Research goal
New targeted treatments
Project
Tipping the scales: How a genetic mutation makes cells unstable
Cancer type
General cancer research
Research goal
How cancer works
Project
Understanding the causes of lymphoma in children
Cancer type
Childhood lymphoma
Research goal
How cancer develops
Project
Visualising the earliest stages of cancer
Cancer type
General cancer research
Research goal
How cancer develops
Project
Understanding how inherited genetic risks are triggered to become leukaemia
Cancer type
Leukaemia
Research goal
How cancer develops
Project
Understanding how colorectal tumours hijack healthy cells
Cancer type
Bowel cancer
Research goal
How cancer works
Project
How immune cells are activated to attack melanoma
Cancer type
Melanoma
Research goal
Improving current treatments
Project
Developing a new model of the immune response to tumours
Cancer type
General cancer research
Research goal
How cancer works
Project
Uncovering how breast cancer recruits healthy cells to grow and spread
Cancer type
Breast cancer
Research goal
How cancer works
Project
Reversing resistance to immune checkpoint inhibitors
Cancer type
Melanoma
Research goal
Overcoming treatment resistance
Project
Developing ultra-sensitive MRI that spots cancer sooner
Cancer type
Breast cancer
Research goal
Improving cancer diagnosis
Project
Resisting resistance: How melanoma cells survive targeted therapy
Cancer type
Melanoma
Research goal
Overcoming treatment resistance
Project
Improving the effect of immunotherapies for melanoma skin cancer
Cancer type
Melanoma
Research goal
Improving current treatment
Project
Unravelling the genetic background of oesophageal cancer
Cancer type
Oesophageal cancer
Research goal
How cancer develops
Project
Epigenetics – exploring one of cancer’s weak spots
Cancer type
General cancer
Research goal
How cancer works
Project
A new ground-breaking approach to bile duct cancer and liver cancer
Cancer type
Liver cancer
Research goal
New targeted therapies

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