Our research projects

We won't stop until cancer does

Project
Stopping cancer becoming resistant to chemotherapy
Cancer type
General cancer research
Research goal
Overcoming treatment resistance
Project
Understanding the role of mutation interactions in oesophageal cancer
Cancer type
Oesophageal cancer
Research goal
How cancer develops
Project
Exploring how the p53 mutation helps cancers spread
Cancer type
General cancer research
Research goal
How cancer develops
Project
Understanding how tissue stiffening affects cancer development
Cancer type
General cancer research
Breast cancer
Lung cancer
Research goal
How cancer works
Project
Protein paradox: finding out how a family of molecules can both help and hinder cancer
Cancer type
Breast cancer
Lung cancer
Research goal
How cancer works
Project
Identifying new treatments for infant leukaemia
Cancer type
Leukaemia
Childhood cancer
Research goal
New targeted treatments
Project
Studying communication between the powerhouse and the brain of the cell to stop cancer growth
Cancer type
Pancreatic cancer
Research goal
How cancer works
Project
Understanding how breast cancer spreads to the bones – and how to stop it
Cancer type
Breast cancer
Research goal
How cancer works
Project
Working together – combining opposing therapies for the greater good
Cancer type
Breast cancer
Research goal
New targeted therapies
Project
Exploring liver cancer's weak spot as a new target for therapy
Cancer type
Liver cancer
Research goal
New targeted treatments
Project
Uncovering how a faulty BRCA2 gene causes breast cancer to develop
Cancer type
Breast cancer
Research goal
How cancer develops
Project
How genetic mutations in healthy blood cells can help drive lymphoma development
Cancer type
Non-Hodgkin lymphoma
Research goal
How cancer works
Project
Understanding why treatments don’t work for some non-smoking lung cancer patients
Cancer type
Lung cancer
Research goal
Overcoming treatment resistance
Project
Using AI to predict drug resistance mutations in breast cancer
Cancer type
Breast cancer
Research goal
Improving diagnosis
Project
Targeting the gut microbiome to make immunotherapies more effective
Cancer type
Bowel cancer
Research goal
How cancer works
Project
Model brains: Using fruit flies to understand how brain tumours spread
Cancer type
Brain
Research goal
How cancer works
Project
Targeting nuclear rupture: a new weakness to exploit in cancer
Cancer type
Breast
Ovarian
General cancer research
Research goal
New targeted treatments
Project
Improving our understanding of how to treat kidney cancer
Cancer type
Kidney
Research goal
How cancer works
Project
Understanding why treatment resistance develops
Cancer type
General cancer research
Research goal
Overcoming treatment resistance
Project
What’s the risk? Predicting endometrial cancer using genetics and measures of obesity
Cancer type
Endometrial cancer
Research goal
Cancer prevention
Project
A new approach to eradicate pancreatic tumours
Cancer type
Pancreatic cancer
Research goal
New targeted treatments
Project
Understanding how melanoma adapts to spread and seed new tumours
Cancer type
Melanoma
Research goal
How cancer works
Project
Understanding how immune cells participate in the spread of pancreatic cancer
Cancer type
Pancreatic cancer
Research goal
How cancer works
Project
Developing a new targeted treatment for lung cancer
Cancer type
Lung cancer
Research goal
New targeted treatments
Project
Blocking bio-parcels to stop breast cancer spreading
Cancer type
Breast cancer
Research goal
New targeted treatments
Project
Tipping the scales: How a genetic mutation makes cells unstable
Cancer type
General cancer research
Research goal
How cancer works
Project
Understanding the causes of lymphoma in children
Cancer type
Childhood lymphoma
Research goal
How cancer develops
Project
Visualising the earliest stages of cancer
Cancer type
General cancer research
Research goal
How cancer develops
Project
Understanding how inherited genetic risks are triggered to become leukaemia
Cancer type
Leukaemia
Research goal
How cancer develops
Project
Understanding how colorectal tumours hijack healthy cells
Cancer type
Bowel cancer
Research goal
How cancer works

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