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Our research projects

We won't stop until cancer does

Project
Using cholesterol to boost anti-tumour T cells
Cancer type
Lung cancer
Melanoma
Research goal
Improve existing treatments
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Project
Target acquired: Making ‘prodrugs’ for neuroblastoma that leave healthy cells unharmed
Cancer type
Neuroblastoma
Research goal
New targeted treatments
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Project
Demystifying what makes melanoma so ‘good’ at resisting treatments
Cancer type
Melanoma
Research goal
Overcoming treatment resistance
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Project
When prevention fails: Understanding how mutated proteins make liver cancer more likely
Cancer type
Liver Cancer
Research goal
How cancer develops
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Project
Finding ways to make immune cells target cancer cells more effectively
Cancer type
General cancer research
Research goal
How cancer works
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Project
Predicting resistance in multiple myeloma and boosting immunotherapy
Cancer type
Multiple Myeloma
Research goal
Overcoming treatment resistance
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Project
Rhythmic radiotherapy: Tackling glioblastoma by changing the interval of treatments
Cancer type
Glioblastoma
Research goal
Improving current treatments
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Project
Seeking kinder treatments for breast cancer
Cancer type
Breast cancer
Research goal
New targeted treatments
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Project
Life, Death and Afterlife: Using cell death to boost our immune system
Cancer type
Breast cancer
Research goal
New targeted treatments
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Project
Stopping cancer becoming resistant to chemotherapy
Cancer type
General cancer research
Research goal
Overcoming treatment resistance
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Project
Understanding the role of mutation interactions in oesophageal cancer
Cancer type
Oesophageal cancer
Research goal
How cancer develops
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Project
Exploring how the p53 mutation helps cancers spread
Cancer type
General cancer research
Research goal
How cancer develops
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Project
Protein paradox: finding out how a family of molecules can both help and hinder cancer
Cancer type
Breast cancer
Lung cancer
Research goal
How cancer works
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Project
Identifying new treatments for infant leukaemia
Cancer type
Leukaemia
Childhood cancer
Research goal
New targeted treatments
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Project
Understanding how tissue stiffening affects cancer development
Cancer type
General cancer research
Breast cancer
Lung cancer
Research goal
How cancer works
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Project
Studying communication between the powerhouse and the brain of the cell to stop cancer growth
Cancer type
Pancreatic cancer
Research goal
How cancer works
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Project
Understanding how breast cancer spreads to the bones – and how to stop it
Cancer type
Breast cancer
Research goal
How cancer works
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Project
Working together – combining opposing therapies for the greater good
Cancer type
Breast cancer
Research goal
New targeted therapies
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Project
Uncovering how a faulty BRCA2 gene causes breast cancer to develop
Cancer type
Breast cancer
Research goal
How cancer develops
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Project
How genetic mutations in healthy blood cells can help drive lymphoma development
Cancer type
Non-Hodgkin lymphoma
Research goal
How cancer works
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Project
Understanding why treatments don’t work for some non-smoking lung cancer patients
Cancer type
Lung cancer
Research goal
Overcoming treatment resistance
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Project
Using AI to predict drug resistance mutations in breast cancer
Cancer type
Breast cancer
Research goal
Improving diagnosis
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Project
Targeting the gut microbiome to make immunotherapies more effective
Cancer type
Bowel cancer
Research goal
How cancer works
Read more
Project
Model brains: Using fruit flies to understand how brain tumours spread
Cancer type
Brain
Research goal
How cancer works
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Project
Targeting nuclear rupture: a new weakness to exploit in cancer
Cancer type
Breast
Ovarian
General cancer research
Research goal
New targeted treatments
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Project
Improving our understanding of how to treat kidney cancer
Cancer type
Kidney
Research goal
How cancer works
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Project
Understanding why treatment resistance develops
Cancer type
General cancer research
Research goal
Overcoming treatment resistance
Read more
Project
What’s the risk? Predicting endometrial cancer using genetics and measures of obesity
Cancer type
Endometrial cancer
Research goal
Cancer prevention
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Project
A new approach to eradicate pancreatic tumours
Cancer type
Pancreatic cancer
Research goal
New targeted treatments
Read more
Project
Understanding how melanoma adapts to spread and seed new tumours
Cancer type
Melanoma
Research goal
How cancer works
Read more

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