Research projects

Complete United Kingdom

Sarcoma

How does the rare tissues cancer sarcoma develop?

Late stage sarcomas remain very hard to treat and not enough is understood about them, so this project hopes to be the starting point for vital new sarcoma cures.

Researcher: Professor Kevin Hiom

Understanding the development of sarcoma – a rare tissue cancer
Vincenzo Constanzo Headshot

Complete Italy

General cancer research

What can we discover about cancer from the placenta?

Researchers hope to find ways for immunotherapy to help more patients by learning how cancer cells hide from the immune system and stopping them hiding. 

Researcher: Dr Vincenzo Costanzo

What can the placenta teach us about cancer?
Sirio Dupont wearing lab coat

Complete Italy

Breast cancer

How can breast cancer be stopped from coming back?

Even if treatment is successful cancer can come back so researchers hope to find new ways to kill even the hidden cancer cells and improve patient outcomes.

Researcher: Dr Sirio Dupont

How can breast cancer be stopped from coming back
Gerard Brien Headshot

Active United Kingdom

Sarcoma

What causes synovial sarcoma, a rare and aggressive cancer?

Many synovial sarcoma tumour patients don’t respond well to treatments so this project wants to find new cures by better understanding what causes it.

Researcher: Dr Gerard Brien

Understanding the cause of synovial sarcoma to improve survival
Grant Dewson in the lab

Complete Australia

Neuroblastoma

Can we find new ways to treat a common childhood cancer?

This project studies how certain mutations drive the development of neuroblastoma and aims to identify new cures - providing hope for families affected.

Researcher: Dr Grant Dewson

Finding new ways to treat neuroblastoma – a common childhood cancer

Complete Italy

Breast cancer

Can we design better treatments for triple-negative breast cancer?

Researchers are developing a highly innovative way to deliver treatments directly to tumours to improve survival rates of aggressive breast cancer.

Researcher: Dr Greta Varchi

Developing a delivery system to improve treatment for aggressive breast cancer
Ruth Ganss Teamshot

Complete Australia

Melanoma

Can our blood vessels help immunotherapy work better for melanoma?

Immunotherapy has helped improve melanoma survival rates but it doesn’t work for everyone so this project hopes to find ways for more patients to benefit.

Researcher: Professor Ruth Ganss

Improving the effect of immunotherapies for melanoma skin cancer
Peter Sarkies Headshot

Complete United Kingdom

General cancer research

What cancers will respond best to treatments that damage their DNA?

Researchers hope to discover which cancers are likely to respond best to different treatment options, to improve patient outcomes in the future.

Researcher: Dr Peter Sarkies

Epigenetics – exploring one of cancer’s weak spots
Mariona Graupera Headshot

Active Spain

Prostate cancer

How can healthy cells contribute to aggressive prostate cancer?

Prostate cancer can be very hard to treat when found at a later stage so this project hopes to pave the way towards future cures for these more aggressive cancers.

Researcher: Dr Mariona Graupera

How can healthy cells contribute to aggressive prostate cancer?