Research projects

Lee Wong and Team

Active Australia

Brain cancer

Can new targeted treatments help treat aggressive brain cancers?

Researchers hope to improve outcomes for brain cancer patients by explore whether tumours with particular mutations can be treated using a targeted therapy 

Researcher: Dr Lee Wong

Tackling tough-to-treat brain cancers with new targeted treatments
Robert Falconer Headshot

Active United Kingdom

Neuroblastoma

Can we target neuroblastoma cells without harming healthy cells?

Lots of cancer drugs cause nasty side effects by affecting healthy cells, so this project is looking for ways to turn on drugs only when they are in the tumour. 

Researcher: Professor Robert Falconer

Target acquired: Making ‘prodrugs’ for neuroblastoma that leave healthy cells unharmed
Peter Carmeliet Team Shot

Active Belgium

Lung cancer

Can we re-wire our cells to help our immune system attack cancer?

Immunotherapy doesn’t always work but researchers hope to find ways to re-wire some of our cells so that these treatments can help more patients in the future.

Researcher: Professor Peter Carmeliet

Rewiring blood cells that block the immune response with AI
Johanna Ivaska Headshot

Active Finland

Breast cancer

Can we stop breast cancer before it spreads to other organs?

Stopping breast cancer spreading would make it much easier to treat so this project is exploring a molecule that appears to stop tumours spreading.

Researcher: Professor Johanna Ivaska

Harnessing the power of healthy breast cells to keep cancer at bay
Alessandro Sartori Teamshot

Active Switzerland

Bowel cancer

Can immunotherapy work for more peoples with bowel cancer?

Immunotherapy for cancer has huge potential but doesn’t always work, so this project hopes to find ways for it to cure more people with bowel cancer.

Researcher: Professor Alessandro Sartori

Developing bowel cancer immunotherapies that target DNA repair
Vincenzo Russo Headshot

Active Italy

Lung cancer

Can cholesterol help immunotherapy work better for cancer patients?

Researchers are looking to increase the quality of life of cancer patients by discovering new ways to boost our immune system to attack cancer.

Researcher: Dr Vincenzo Russo

Using cholesterol to boost anti-tumour T cells
Pau Sancho Bru Headshot

Active Spain

Liver cancer

How does liver cancer grow in children and how can we stop it?

Looking for new cures for hepatoblastoma, the most common type of liver cancer in children, by studying ‘mini tumours’ to discover how it develops. 

Researcher: Dr Pau Sancho-Bru

Growing mini tumours in the lab to understand hepatoblastoma
Fulvio Chiacchiera Headshot

Active Italy

Liver cancer

How do mutated proteins make liver cancer more likely?

Researchers are hoping to discover new ways to diagnose liver cancer more accurately, which would help patients receive better treatments more quickly.

Researcher: Dr Fulvio Chiacchiera

When prevention fails: Understanding how mutated proteins make liver cancer more likely
Stefano Angiari Headshot

Active Austria

Lung cancer

How do cancer cells stop immune cells from doing their job?

This project could lead to new immunotherapy treatments that can block tumour growth in lung cancer and potentially many other cancer types.

Researcher: Dr Stefano Angiari

Turning red lights green: How do cancer cells stop immune cells from doing their job?