Research projects

Katrin Ottersbach in the lab

Active United Kingdom

Leukaemia

How does infant leukaemia develop and how can we stop it?

Infant leukaemia is very difficult to treat so researchers are hoping to better understand its unique biology to reveal vital better and kinder treatments.

Researcher: Professor Katrin Ottersbach

Identifying new treatments for infant leukaemia
Jamie Rossjohn Headshot

Active Australia

Leukaemia

Can we help immunotherapies treat leukaemia better?

This project hopes to reveal new, better, immunotherapy treatments for leukaemia by boosting a different cell in our immune system from other treatments. 

Researcher: Professor Jamie Rossjohn

Revealing the role of natural killer cells in cancer immunity
Inbal Wortzel Headshot

Active USA

Multiple cancers

What makes it easier for some cancers to spread to other organs?

Exploring how ‘messages’ sent from cancer cells to other parts of the body might help cancers to spread and whether new cures could stop this process.

Researcher: Dr Inbal Wortzel

A new way to predict and treat the spread of cancer
Lee Wong and Team

Active Australia

Brain cancer

Can new targeted treatments help treat aggressive brain cancers?

Researchers hope to improve outcomes for brain cancer patients by explore whether tumours with particular mutations can be treated using a targeted therapy 

Researcher: Dr Lee Wong

Tackling tough-to-treat brain cancers with new targeted treatments
Robert Falconer Headshot

Active United Kingdom

Neuroblastoma

Can we target neuroblastoma cells without harming healthy cells?

Lots of cancer drugs cause nasty side effects by affecting healthy cells, so this project is looking for ways to turn on drugs only when they are in the tumour. 

Researcher: Professor Robert Falconer

Target acquired: Making ‘prodrugs’ for neuroblastoma that leave healthy cells unharmed
Peter Carmeliet Team Shot

Active Belgium

Lung cancer

Can we re-wire our cells to help our immune system attack cancer?

Immunotherapy doesn’t always work but researchers hope to find ways to re-wire some of our cells so that these treatments can help more patients in the future.

Researcher: Professor Peter Carmeliet

Rewiring blood cells that block the immune response with AI
Johanna Ivaska Headshot

Active Finland

Breast cancer

Can we stop breast cancer before it spreads to other organs?

Stopping breast cancer spreading would make it much easier to treat so this project is exploring a molecule that appears to stop tumours spreading.

Researcher: Professor Johanna Ivaska

Harnessing the power of healthy breast cells to keep cancer at bay
Alessandro Sartori Teamshot

Active Switzerland

Bowel cancer

Can immunotherapy work for more peoples with bowel cancer?

Immunotherapy for cancer has huge potential but doesn’t always work, so this project hopes to find ways for it to cure more people with bowel cancer.

Researcher: Professor Alessandro Sartori

Developing bowel cancer immunotherapies that target DNA repair
Vincenzo Russo Headshot

Active Italy

Lung cancer

Can cholesterol help immunotherapy work better for cancer patients?

Researchers are looking to increase the quality of life of cancer patients by discovering new ways to boost our immune system to attack cancer.

Researcher: Dr Vincenzo Russo

Using cholesterol to boost anti-tumour T cells