Research projects

Staffan Stromblad Team Shot

Active Sweden

Multiple cancers

How does ‘tissue stiffening’ affect cancer development?

This project hopes to discover more about the biology of how solid tumours develop to find new ways to prevent, diagnose or treat these cancers.

Researcher: Professor Staffan Stromblad

Understanding how 'tissue stiffening' affects cancer development
Leandro Sastre Garzon and Team

Active Spain

Head & neck cancer

How do the cells around tumours help head and neck cancers to spread?

Researchers hope to find new ways to stop cancer by better understanding how the ‘tumour microenvironment’ around cancers impacts their ability to spread. 

Researcher: Professor Leandro Sastre Garzón

Uncovering how the tumour microenvironment can make cancer cells more aggressive
Tomer Cooks and Team

Active Israel

General cancer research

How does one of the most common cancer mutations help cancer spread?

Researchers hope to find new ways predict and stop cancers becoming life-threatening by understanding how a very common cancer mutation helps cancers spread.

Researcher: Dr Tomer Cooks

Exploring how the p53 mutation helps cancers spread
Seth Coffelt in the lab

Active United Kingdom

Pancreatic cancer

How do immune cells participate in the spread of pancreatic cancer?

This project hopes to find vital new treatments for pancreatic cancer patients with no current options by better understanding how pancreatic cancers spreads.

Researcher: Professor Seth Coffelt

Understanding how immune cells participate in the spread of pancreatic cancer
Lorenza Penengo Team in the lab

Complete Switzerland

General cancer research

Why does combination treatment stop working for some cancer patients?

This project hopes to discover new ways to prevent the development of resistance to cancer treatments which is crucial to stop people dying from cancer. 

Researcher: Professor Lorenza Penengo

Understanding why treatment resistance develops
Sakari Vanharanta Headshot

Active Finland

Kidney cancer

How does kidney cancer develop and how can we stop it?

By studying the mechanisms that drive the growth of kidney cancer researchers are hoping to discover vital new ways to prevent it progressing and spreading.

Researcher: Dr Sakari Vanharanta

Improving our understanding of how to treat kidney cancer
Aura Carreira Headshot

Active Spain

Breast cancer

How does a faulty BRCA2 gene cause breast cancer to develop?

The team hope that by understanding how different mutations contribute to breast cancer, they can reveal new ways to prevent, diagnose and treat it.  

Researcher: Dr Aura Carreira

Uncovering how a faulty BRCA2 gene causes breast cancer to develop
Stefano Biffo and Team

Active Italy

General cancer research

Can we stop cancers hiding from our immune systems?

This project hopes to discover clues about new ways to provide personalised immunotherapy treatments for patients with many different cancer types.  

Researcher: Professor Stefano Biffo

Developing a new model of the immune response to tumours
Luigi Nezi and Team

Active Italy

Bowel cancer

Can the gut microbiome help make immunotherapies more effective?

By studying the microbes living in the guts bowel cancer patients researchers hope to reveal new ways to make immunotherapies more effective.

Researcher: Dr Luigi Nezi

Targeting the gut microbiome to make immunotherapies more effective