Research projects

Seth Coffelt in the lab

Active United Kingdom

Pancreatic cancer

How do immune cells participate in the spread of pancreatic cancer?

This project hopes to find vital new treatments for pancreatic cancer patients with no current options by better understanding how pancreatic cancers spreads.

Researcher: Professor Seth Coffelt

Understanding how immune cells participate in the spread of pancreatic cancer
Lorenza Penengo Team in the lab

Complete Switzerland

General cancer research

Why does combination treatment stop working for some cancer patients?

This project hopes to discover new ways to prevent the development of resistance to cancer treatments which is crucial to stop people dying from cancer. 

Researcher: Professor Lorenza Penengo

Understanding why treatment resistance develops
Sakari Vanharanta Headshot

Active Finland

Kidney cancer

How does kidney cancer develop and how can we stop it?

By studying the mechanisms that drive the growth of kidney cancer researchers are hoping to discover vital new ways to prevent it progressing and spreading.

Researcher: Dr Sakari Vanharanta

Improving our understanding of how to treat kidney cancer
Aura Carreira Headshot

Active Spain

Breast cancer

How does a faulty BRCA2 gene cause breast cancer to develop?

The team hope that by understanding how different mutations contribute to breast cancer, they can reveal new ways to prevent, diagnose and treat it.  

Researcher: Dr Aura Carreira

Uncovering how a faulty BRCA2 gene causes breast cancer to develop
Stefano Biffo and Team

Active Italy

General cancer research

Can we stop cancers hiding from our immune systems?

This project hopes to discover clues about new ways to provide personalised immunotherapy treatments for patients with many different cancer types.  

Researcher: Professor Stefano Biffo

Developing a new model of the immune response to tumours
Luigi Nezi and Team

Active Italy

Bowel cancer

Can the gut microbiome help make immunotherapies more effective?

By studying the microbes living in the guts bowel cancer patients researchers hope to reveal new ways to make immunotherapies more effective.

Researcher: Dr Luigi Nezi

Targeting the gut microbiome to make immunotherapies more effective

Active Italy

General cancer research

Can we visualise the earliest stages of cancer developing?

Researchers hope to discover whole new ways to prevent and treat cancer in the future by using a powerful new technique to study how cancer grows.

Researcher: Dr Davide Mazza

Visualising the earliest stages of cancer
Victoria Sanz Moreno in the Lab

Active United Kingdom

Melanoma

How does melanoma adapt to spread and seed new tumours?

Cancers is easier to treat when caught early so this project hopes to reveal new treatments that could stop melanoma spreading, helping survival rates.

Researcher: Professor Victoria Sanz-Moreno

Understanding how melanoma adapts to spread and seed new tumours

Active Italy

General cancer research

How does a genetic mutation make cells unstable and cancerous?

Mutations to a certain gene lead to several types of cancer, so this project hopes to find new future cures by better understanding the role of this mutation.

Researcher: Dr Diego Pasini

Tipping the scales: How a genetic mutation makes cells unstable