Research projects

Pau Sancho Bru Headshot

Active Spain

Liver cancer

How does liver cancer grow in children and how can we stop it?

Looking for new cures for hepatoblastoma, the most common type of liver cancer in children, by studying ‘mini tumours’ to discover how it develops. 

Researcher: Dr Pau Sancho-Bru

Growing mini tumours in the lab to understand hepatoblastoma
Fulvio Chiacchiera Headshot

Active Italy

Liver cancer

How do mutated proteins make liver cancer more likely?

Researchers are hoping to discover new ways to diagnose liver cancer more accurately, which would help patients receive better treatments more quickly.

Researcher: Dr Fulvio Chiacchiera

When prevention fails: Understanding how mutated proteins make liver cancer more likely
Stefano Angiari Headshot

Active Austria

Lung cancer

How do cancer cells stop immune cells from doing their job?

This project could lead to new immunotherapy treatments that can block tumour growth in lung cancer and potentially many other cancer types.

Researcher: Dr Stefano Angiari

Turning red lights green: How do cancer cells stop immune cells from doing their job?
Philippe Pasero and Team

Active France

Multiple myeloma

Why do some myeloma patients respond better to treatment?

Multiple myeloma is a hard to treat blood cancer and so in this project researchers want to find ways to help immunotherapy work for more patients.

Researcher: Dr Philippe Pasero

Predicting resistance in multiple myeloma and boosting immunotherapy
Maria Alcolea Team

Active United Kingdom

Oesophageal cancer

How do mutations interact to cause oesophageal cancer?

By better understanding how oesophageal cancer first emerges researchers hope to find new ways to prevent this disease and improve survival rates. 

Researcher: Dr Maria Alcolea

Understanding the role of mutation interactions in oesophageal cancer
Loredana Saveanu Headshot

Active France

General cancer research

How does our immune system interact with cancer cells?

Immunotherapy doesn’t always work but by learning more about how immune cells and cancer cells interact researchers hope it can work better for more patients.

Researcher: Dr Loredana Saveanu

Finding ways to make immune cells target cancer cells more effectively
Pierre Close and Team

Active Belgium

Melanoma

What makes melanoma so good at resisting treatments?

Therapies for melanoma sometimes stop working if treatment resistance develops so by understanding how this happens researchers hope to find new, better, cures. 

Researcher: Dr Pierre Close

Demystifying what makes melanoma so ‘good’ at resisting treatments
Olivier Pardo and Team

Active United Kingdom

Multiple cancers

How can the same molecule both help and hinder cancer?

Lung cancer and breast cancer cells behave very differently so by exploring the unique ways their cells communicate researchers hope to find better cures.

Researcher: Dr Olivier Pardo

Protein paradox: finding out how a family of molecules can both help and hinder cancer
Jamie Dean and Team

Active United Kingdom

Brain cancer

Could changing the timing of radiotherapy help it work better?

This project hopes to reveal if changing the intervals between radiotherapy doses makes it better at treating one of the most common types of brain tumour.

Researcher: Dr Jamie Dean

Rhythmic radiotherapy: Tackling glioblastoma by changing the interval of treatments